Protein Quality Control in Neurodegenerative Diseases
Eric Guisbert, Richard I. Morimoto (auth.), Richard I. Morimoto, Yves Christen (eds.)The health of the proteome depends upon protein quality control to regulate the proper synthesis, folding, translocation, and clearance of proteins. The cell is challenged constantly by environmental and physiological stress, aging, and the chronic expressions of disease associated misfolded proteins. Substantial evidence supports the hypothesis that the expression of damaged proteins initiates a cascade of molecular events that leads to Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis, Huntington's disease, and other diseases of protein conformation.
Thể loại:
Năm:
2013
In lần thứ:
1
Nhà xuát bản:
Springer-Verlag Berlin Heidelberg
Ngôn ngữ:
english
Trang:
136
ISBN 10:
3642279287
ISBN 13:
9783642279287
Loạt:
Research and Perspectives in Alzheimer's Disease
File:
PDF, 1.96 MB
IPFS:
,
english, 2013
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